Prediabetes is associated with abnormal circadian blood pressure variability

A.K. Gupta, F.L. Greenway, G. Cornelissen, W. Pan and .F Halberg

Prediabetes is associated with abnormal circadian blood pressure variability

Abstract: «Blood pressure (BP) exhibits a circadian variation characterized by a morning increase, followed by a small postprandial valley and a deeper descent during nocturnal rest. Although abnormal 24-h variability (abnormal circadian variability (ACV)) predicts adverse cardiovascular disease (CVD) outcomes, a 7-day automatic ambulatory BP monitoring (ABPM) and subsequent chronobiologic analysis of the gathered data, permits identification of consistency of any abnormal circadian variation. To test whether normal overweight healthy men and women with prediabetes differed from subjects with normoglycemia in having ACV with a 7-day ABPM…»

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